Dental Pulp Stem Cell Recruitment Signals within Injured Dental Pulp Tissue
نویسندگان
چکیده
منابع مشابه
Dental Pulp Stem Cell Recruitment Signals within Injured Dental Pulp Tissue
The recruitment of dental pulp stem cells (DPSC) is a prerequisite for the regeneration of dentin damaged by severe caries and/or mechanical injury. Understanding the complex process of DPSC recruitment will benefit future in situ tissue engineering applications based on the stimulation of endogenous DPSC for dentin pulp regeneration. The current known mobilization signals and subsequent migrat...
متن کاملDental pulp tissue engineering.
Dental pulp is a highly specialized mesenchymal tissue that has a limited regeneration capacity due to anatomical arrangement and post-mitotic nature of odontoblastic cells. Entire pulp amputation followed by pulp space disinfection and filling with an artificial material cause loss of a significant amount of dentin leaving as life-lasting sequelae a non-vital and weakened tooth. However, regen...
متن کاملStem Cells of the Dental Pulp
Dental Pulp Stem Cells (DPSCs) can be found within the cell rich zone of dental pulp. These stem cells, under specific stimuli, differentiate into many cell types which have wide therapeutic applications. The dental stem cells are derived from both deciduous and permanent teeth. The viable dental stem cells are very simple to collect, without any mortality and morbidity. Dental pulp stem c...
متن کاملMonitoring Notch Signaling-Associated Activation of Stem Cell Niches within Injured Dental Pulp
Dental pulp stem/progenitor cells guarantee tooth homeostasis, repair and regeneration throughout life. The decision between renewal and differentiation of these cells is influenced by physical and molecular interactions with stromal cells and extracellular matrix molecules forming the specialized microenvironment of dental pulp stem cell niches. Here we study the activation of putative pulp ni...
متن کاملDental pulp as a stem cell reservoir.
Currently, much information is provided regarding the presence and the roles in tissue regeneration of stem cell niches residing in post-natal dental pulp. So far, three types of adult stem cells have been isolated from dental pulp. Correct evaluation of these cells is important in order to determine their potential use in clinical fields. The present study aims to review the origins and immuno...
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ژورنال
عنوان ژورنال: Dentistry Journal
سال: 2016
ISSN: 2304-6767
DOI: 10.3390/dj4020008